Cancer and fecundity issues mandate a multidisciplinary approach.
Auteurs : de Ziegler D, Streuli I, Vasilopoulos I, Decanter C, This P, Chapron C
Date de publication : 02/2010
Résumé vulgarisé
OBJECTIVE: To review the existing options for preserving fecundity in young cancer patients, outlining the differences that exist in each individual cancer situation and how these affect our choice of fecundity-preserving measures. DESIGN: Review the pathophysiology data on ovarian function that serve for outlining the advantages and/or drawbacks of certain fecundity-preserving measures such as ovarian freezing and emergency IVF. Provide support arguments for outlining the need for setting locally rooted cancer and fecundity task forces that throw the bases for a multidisciplinary approach in this field. SETTING: Review of literature data. PATIENT(S): Women of reproductive age affected with different types of cancer. MAIN OUTCOME MEASURE(S): Outcome of selected emergency fertility preserving measures such as ovarian tissue freezing followed by grafting or emergency IVF. RESULT(S): When performed in the 30s-the typical age for breast cancer, the most frequently encountered cancer in women of reproductive age, ovarian freezing hampers ovarian recovery and the chances for spontaneous pregnancy. CONCLUSION(S): Based on a review of the different situations encountered, we recommend that fecundity-preserving measures offered to young cancer patients, including ovarian freezing and emergency IVF, emanate from multidisciplinary approaches.
