Absence of association between a functional polymorphism of ALOX15 gene and infertility in endometriosis.
Auteurs : Borghese B, Gayet V, Chiche JD, Vernerey D, de Ziegler D, BonaitiPellié C, Chapron C
Date de publication : 04/2009
Résumé vulgarisé
The aim of the present study, involving 463 women of reproductive age, was to evaluate for the first time the relationship between endometriosis, endometriosis-related infertility, and a recently described functional polymorphism in the ALOX15 gene, reported to be essential for implantation. In our study population, ALOX15 -292 C/T was not correlated either with the risk of developing an endometriosis or with the risk of infertility.